Product Notes
- 7859383 reads
A new and efficient method for the homologation of urethane protected α-amino acids to its β-homomers by the Arndt-Eistert method using TBTU as a coupling agent is described. Several Fmoc-/Boc-/Z-protected α-amino diazoketone derivatives have been obtained as crystalline solids in good yield. The method is found to be rapid and stereospecific.
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