Short Description::
Long Description::
HBTU is a standard coupling agent commonly used for the activation of free carboxylic acids during the solution and solid phase peptide synthesis. 1-Hydroxybenzotriazole (HOBt) plays a significant role in reducing the racemization during peptide synthesis; hence it is regularly used as a coupling additive.
Application::
HBTU is a standard coupling agent commonly used for the activation of free carboxylic acids during the solution and solid phase peptide synthesis. 1-Hydroxybenzotriazole (HOBt) plays a significant role in reducing the racemization during peptide synthesis; hence it is regularly used as a coupling additive.
Dose::
Note::
N-Hydroxybenzotriazole (HOBt) has classically been used as a catalyst for peptide coupling to minimize racemization and O- to N-acyl transfer (Figure 9.6) through formation of the active ester. Unfortunately HOBt is known to react violently, especially when dry, and the shipping of HOBt is restricted
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Product remark::
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Useful Area::
Related Information::
N-Hydroxybenzotriazole (HOBt) has classically been used as a catalyst for peptide coupling to minimize racemization and O- to N-acyl transfer (Figure 9.6) through formation of the active ester. Unfortunately HOBt is known to react violently, especially when dry, and the shipping of HOBt is restricted
RXMARINE CHEMICAL TAG::