Glycine has buffering capacity and hence acts as an osmoprotectant for cells in culture. It participates in majority of anabolic reaction such as synthesis of heme, creatine and glutathione. Besides these, the glycine cleavage pathway is found to be associated with cell proliferation of several human tumor cell lines. Presence of glycine in conditioned medium enhances the growth of mouse and cattle embryos. Since glycine acts as an inhibitory neurotransmitter in brain and spinal cord, it is a prime target of many neuro psycho pharmacologic agents.