ETHYL OLEATE FOR SYNTHESIS 98%
SKU:
SKU
RXSOL-60-6604-568
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Category
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Short Description
Short Description
ETHYL OLEATE FOR SYNTHESIS 98%
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Also known as
ETHYL OLEATE FOR SYNTHESIS 98%
Product Description
Ethyl oleate uses Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids. It also finds use as a lubricant and a plasticizer.
Application
- E 1625 (OTTO) Ethyl oleate, 99% Cas 111-62-6 - used to prepare the oily phase of self-microemulsifying drug delivery system (SMEDDS) for tacrolimus (Tac).
Note
Note
- The ethyl oleate used by the submitters was prepared by esterification of commercial U.S.P. grade oleic acid and fractionated through a Widmer column. The fraction boiling at 160–170°/1 mm., nD25 1.4482–1.4570, iodine value 83.6 (calculated 81.8), was used.
- The purity of the absolute ethanol is of prime importance. Ethanol dried only by a lime process gives a low yield (20–25%). The ethanol used in this procedure was dried over lime and then over aluminum tert-butoxide, after which it was distilled directly into the flask used for the reaction.
- The submitters used a modified Widmer column; the checkers, a Claisen flask modified with a short Vigreux column.
Product Remark
Remarks
Related Information
Note
- The ethyl oleate used by the submitters was prepared by esterification of commercial U.S.P. grade oleic acid and fractionated through a Widmer column. The fraction boiling at 160–170°/1 mm., nD25 1.4482–1.4570, iodine value 83.6 (calculated 81.8), was used.
- The purity of the absolute ethanol is of prime importance. Ethanol dried only by a lime process gives a low yield (20–25%). The ethanol used in this procedure was dried over lime and then over aluminum tert-butoxide, after which it was distilled directly into the flask used for the reaction.
- The submitters used a modified Widmer column; the checkers, a Claisen flask modified with a short Vigreux column.
Supply Location
Locations
[ETHYL OLEATE FOR SYNTHESIS 98%] manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman.
Lab chemicals manufacturers, suppliers, exporters in India, UAE Middle East, Barka, Sohar, Muscat, Oman, Canada.
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